Could 2 or more of this be dumped in main drain lateral to city line to open a significant grease clog?

Yes. For Laterals: Pour 1 gallon (that would be 4 bottles of this product) into drain upstream and as close to the obstruction as possible. For Sewer Mains: Pour 2-4 gallons (8 to 16 bottles of this product) into manhole or drain upstream and as close to the obstruction as possible. For best results, use regularly to keep sewer main open and free flowing
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